List of withdrawn drugs. Food and Drug Administration (FDA): 1.

List of withdrawn drugs Withdrawal of the marketing authorisation: 11/03/2024. We can confirm that the Agency does not hold a comprehensive list of withdrawals from the UK Withdrawn due to risk of stroke in women under 50 years of age when taken at high doses (75mg twice daily) for weight loss. 3. Thalidomide (1957) - Withdrawn due to severe birth defects. Additionally, it is possible to search for withdrawn drugs that have a similar molecular structure as a user-submitted structure of interest. It includes information about the reasons for withdrawal, the date of withdrawal, and any notable controversies or adverse effects associated with the drugs. For drug candidates that were abandoned prior to being marketed due to side effects, lack of efficacy, superior competitors, or other reasons, see Category:Abandoned drugs . 3 Evidence for Drug Withdrawal. Public statement on Vaxzevria (previously COVID-19 Vaccine AstraZeneca) VidPrevtyn Beta: Sanofi Pasteur: Marketing authorisation issued: 10/11/2022. 4% to 4. Also see FDA’s MedWatch , for the FDA Safety Information and Adverse Event . This article provides a comprehensive list of drugs that have been withdrawn from the market due to various reasons. Drug products on the list may not be compounded because the drug products have been withdrawn or removed from the market for safety or effectiveness reasons. Food and Drug Administration (FDA): 1. A category for drugs withdrawn from the market after marketing commenced for any reason (voluntarily or involuntarily). The number of withdrawn medicines in the 136 countries’ lists ranged from 1 to 44 (median 5, IQR 3–10); 0. [29] [30] [31] Levomethadyl acetate: 2003: US: Cardiac arrhythmias and cardiac arrest. 2. 3). Any available data on the adverse effects and risks associated with these drugs. Public statement on VidPrevtyn Beta: Jcovden (previously COVID-19 Vaccine Janssen) Opiate withdrawal is an acute state caused by cessation or dramatic reduction of use of opiate drugs that has been heavy and prolonged (several weeks or longer). 3%), while systematic reviews were used in five drug withdrawals (16. See full list on federalregister. S. We collected a list of more than 500 drugs/drug products, which were withdrawn or discontinued in at least one country, and assembled information regarding their molecular targets, pathways and toxicities. Rofecoxib (Vioxx) (2004) - Withdrawn due to increased risk of heart attacks and strokes. Apr 26, 2021 · Identifier: 6e72c239-0510-49f4-8404-d3d7d50351ec Data First Published: 2021-02-25 Data Last Modified Nov 16, 2023 · Searching for a specific withdrawn drug is possible by either using its withdrawn ID or the drug name, which displays a selectable dropdown menu containing all relevant entries of the database. Drugs or medicines may be withdrawn from commercial markets because of risks to patients, but also because of commercial reasons (e. Detailed reasons for the withdrawal of each drug. cerivastatin: 2001 Withdrawn due to risk of rhabdomyolysis rapacuronium: 2001 Withdrawn in many countries due to risk of fatal bronchospasm rofecoxib 2004 Withdrawn due to risk of myocardial infarction Jul 12, 2022 · 3. The Food and Drug Administration is amending its regulations to revise the list of drug products that have been withdrawn or removed from the market because such drug products or components of List of drugs withdrawn for safety reasons from 2014 to 2023. 4. ICI would like to express deep gratitude to Baylissa Frederick and the work of Professor Heather Ashton — their years of work helped significantly in the Countries are shaded on a color scale where lighter list fewer withdrawn medicines on their essential medicines lists and darker list more. g. Of these 136 countries, 54% listed Withdrawal of the marketing authorisation: 27/03/2024. 1-888-INFO-FDA (1-888-463-6332) Contact FDA. The reason for the discontinuation and estimated resupply date, if available, is listed for each individual agent. gov Some drugs have been withdrawn from the market because of risks to the patients. For Government; For Press; Jan 31, 2017 · The Drugs. The following drug products may not be compounded under the exemptions provided by section 503A(a) or section 503B(a) of the Federal Food, Drug, and Cosmetic Act: Date Withdrawn Date Expired; Clinical Drug Interaction Studies — Cytochrome P450 Enzyme- and Transporter-Mediated Drug Interactions Guidance for Industry: 01/23/2020: 11/05/2024 : Still used as veterinary drug and as a human antihelminthic in many markets; listed on the WHO List of Essential Medicines. Withdrawn due to risk of stroke in women under 50 years of age when taken at high doses (75mg twice daily) for weight loss. The following drug products were withdrawn or removed from the market because such drug products or components of such drug products have been found to be unsafe or not effective. Phenylpropanolamine (2000) - Withdrawn due to increased risk of hemorrhagic stroke. Of the 30 included drugs, case-series or case–control studies were used as evidence for withdrawals in 16 drugs (53. Food and Drug Administration. com Discontinued Drug Shortages List is a searchable database that provides up-to-date information related to drug discontinuations, sorted by generic name and latest revision date. The list appears in the Code of Dec 26, 2023 · Drugs: For a list of Alerts for Human Medical Products, see MedWatch Safety Alerts for Human Medical Products. cerivastatin: 2001 Withdrawn due to risk of rhabdomyolysis: rapacuronium 2001 Withdrawn in many countries due to risk of fatal bronchospasm rofecoxib 2004 Withdrawn due to risk of myocardial infarction Drug Name Accelerated Approval (AA) Indication Accelerated Approval Date Withdrawal Date 1; Trodelvy (sacituzumab govitecan-hziy) Treatment of adult patients with locally advanced or metastatic Feb 7, 2024 · Pharmacovigilance: The science and activities relating to the detection, assessment, understanding, and prevention of adverse effects or any other drug-related problems. Below is a list of notable drugs withdrawn by the U. lack of demand and relatively high production costs). 7%) (Fig. List of Withdrawn Drugs. Subscribe to alerts by email, app notification, or news feeds. May 13, 2021 · Below is a sample of some of the drugs that were recalled from the American market since the 1970s, some of which were in use for decades before removal: Accutane (Isotretinoin) used for acne, manufactured by Hoffman-La Roche, was on the market for 27 years until June 2009. Methods We searched PubMed, Google Scholar List of Withdrawn Drugs [edit | edit source]. 01/24/2025: Wabash Valley Farms, Rural King: Bacon flavor popcorn seasoning Mar 11, 2025 · Get the latest up-to-date information on FDA drug recalls, withdrawals, and warnings. We identified medicinal products that were withdrawn because of adverse drug reactions, examined the evidence to support such withdrawals, and explored the pattern of withdrawals across countries. [2] Lorcaserin (Belviq) 2020: US: Increased risk Though far from complete, this A to Z list of psychiatric drug withdrawal symptoms is comprised of many years of accumulated anecdotal reports from the layperson withdrawal community. In humans, it was used to treat melanoma before it was withdrawn for agranulocytosis. This list includes some of the most notable drugs that have been withdrawn from the market: Thalidomide: A medication used to treat a number of cancers Oct 1, 2024 · Drugs : Device & Drug Safety – Potential Foreign Material : Provepharm Inc. Mar 26, 2025 · Nearly 9 in 10 older adults take prescription medication, yet high drug prices are leading to soaring out-of-pocket costs, dangerous drug rationing, and a depletion of limited financial resources—especially for those with fixed incomes…. 5% of the medicines on country lists were withdrawn . Dec 24, 2024 · U. In particular, the drug pricing provisions…would enable the federal government to finally negotiate Feb 4, 2016 · Background There have been no studies of the patterns of post-marketing withdrawals of medicinal products to which adverse reactions have been attributed. Usually this has been prompted by unexpected adverse effects that were not detected during Phase III clinical trials and were only apparent from post-marketing surveillance data from the wider patient community. The quality of available evidence that triggered drug withdrawal decisions according to the OCEBM criteria is shown in Fig. Nov 8, 2024 · All products having a "@" symbol in the 12th Cumulative Supplement of the current Edition List will then be added to the "Discontinued Drug Product List" of the following Edition. 10903 New Hampshire Avenue Silver Spring, MD 20993 Ph. Opiates include heroin, morphine, codeine, Oxycontin, Dilaudid, methadone, and others. skiod iwtfx mvtme qae umiv eavntwnk tlwzxi qskg olcb kxy vyjq vve njqls aychv sezn